Influenza burden in frail elderly

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CYP2D6 Metabolism in Frail Elderly Compared to Non-Frail Elderly: A Pilot Feasibility Study

BACKGROUND Frailty is a clinical phenotype that is associated with adverse health outcomes. Since frail patients may be more prone for adverse drug events and about 15-20 % of commonly prescribed drugs are metabolized by CYP2D6, we hypothesized that CYP2D6 metabolism is decreased in frail patients compared with healthy subjects. METHODS The (13)C-dextromethorphan breath test (DM-BT) was used ...

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Nutritional status of frail elderly

__________________________________________________________________________ Introduction: Growing population of elderly requires effective medical diagnostics and help. Criteria developed by Fried et al. are most often used for the diagnosis of the frailty syndrome. An inherent element of frailty syndrome is malnutrition. Malnutrition results from inadequate food supply, coexistence of acute and...

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ژورنال

عنوان ژورنال: The Lancet Respiratory Medicine

سال: 2018

ISSN: 2213-2600

DOI: 10.1016/s2213-2600(17)30442-3